Natasha Lukoyanova

Department of Biological Sciences


Birkbeck College 

London WC1E 7HX, UK



EM facility ISMB/Birkbeck

Birkbeck EMBO course 2021

Wellcome/MRC training in cryoEM


Dr Lukoyanova is the EM facility co-ordinator at the Institute of Structural and Molecular Biology (ISMB). She oversee the day to day operation of the Titan Krios and other equipment in the facility, trains users on sample preparation, assists with data collection and image processing. She is also actively involved in data collection at the national Electron Bio-Imaging Centre (eBIC) at Diamond.

Together ewith colleagues from ISMB Birkbeck EM group she organises and teaches at biannual EMBO courses on EM image processing at Birkbeck. In collaboration with colleagues from The Astbury Biostructure Lab (University of Leeds), eBIC (Diamond light source), Scottish Centre for Macromolecular Imaging (University of Glasgow) and Midlands Regional Cryo-EM Facility (University of Leicester) she is also participates in Community lead Cryo-EM Training program funded by Wellcome and MRC (218785/Z/19/Z).

Her resent research (collaboration with Prof. C. Kleanthous, University of Oxford) focuses on the formation of E. coli outer membrane ColE9 translocon complex (DOI: 10.15252/embj.2021108610 ) and structure of lymphocyte perforin pore (DOI: 10.1126/sciadv.abk3147 )

Please visit ORCID for a publication  list.

Before becoming facility co-ordinator, she was a senior postdoc in Prof. H. Saibil’s group (Birkbeck). In this role, she was responsible for the EM component of a multidisciplinary study of the molecular mechanisms of membrane disruption by MACPF/CDC pore-forming proteins. Previously, she studied the structure of septin filaments with Prof. J. Trinick (University of Leeds) and actin and actin binding proteins during her postdoctoral training under Prof. E. Egelman (University of Virginia).