ยท  S. Raghunathan, A.G. Kozlov, T.M. Lohman, and G. Waksman.
Structure of the DNA binding domain of E.coli SSB bound to ssDNA.

 

Nature Structural Biology. 7:648-652. (2000)


The structure of the DNA binding domain of the single-stranded DNA binding protein from Escherichia coli (Eco SSB) bound to two 35-mer ssDNAs was determined to a resolution of 2.8 _. This structure describes the vast network of interactions that results in the extensive wrapping of ssDNA around the SSB tetramer and suggests a structural basis for its various binding modes.

 

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