| Professor of Biomolecular Science Crystallography , Dept of Biological Sciences Birkbeck College Malet Street LONDON WC1E 7HX Office: +44-20-7631-6852 |
 description |
| Professor of Biomolecular Science Crystallography , Dept of Biological Sciences Birkbeck College Malet Street LONDON WC1E 7HX Office: +44-20-7631-6852 |
description |
Executive Dean of the School of Science and Professor of Biomolecular Science.
Member of the Institute for Structural Molecular Biology
Academic Staff Representative Governor
2001-2006
President of Birkbeck College AUT AUT 2001-2004 Vice-President 2004-2005
I am the Senior Tutor on the MSc in Structural Biology Using the Internet
and the Advanced Certificate in Techniques in Structural
Molecular Biology
I am a member of the Department Research
Students Committee and organise the students progress evaluations. I am also Ph.D. admissions
Tutor.
Other lectures to Ph.D. students can be
found here (Department
only)
Group
Simon Edwards Ph.D. Student 1998-2001
Halina Garavini Ph.D. Student 1999-2003
David Knight Ph.D. Student 2000-2004
Ritu Garg Part-time Ph.D. Student 2001-2007
Chris Kennaway Ph.D. Student 2002-2005
Pryank Patel Ph.D. Student 2004-2007
Gemma Gargent MRes/Ph.D. Student 2005-2010
Francois-Xavier Chauviac Ph.D. Student 2007-
Laura Hancock Part-time Ph.D. Student 2007-2010
Eugen Strehle Part time M.Phil. Student 2002-2004
Dr Anne Nicolas Postdoc 2001-2003
Dr Martin Cohen-Gonsaud Postdoc 2002-2005
Dr Giles Robertson Postdoc 2006-2009
I also supervise Cancer Research Technology staff based at Birkbeck
currentlyDr Andrew Turnbull and Nicola Evans
Basavannacharya, C., Robertson, G., Munshi, T., Keep, N.H. & Bhakta, S. (2010). ATP-dependent MurE ligase in Mycobacterium tuberculosis: Biochemical and structural characterisation. Tuberculosis 90, 16-24.
Bagneris, C., Bateman, O.A., Naylor, C.E., Cronin, N., Boelens, W.C., Keep, N.H. & Slingsby, C. (2009). Crystal structures of alpha-crystallin domain dimers of alphaB-crystallin and Hsp20. J. Mol. Biol. 392, 1242-1252.
Zhou J.J., Robertson G., He X., Dufour, S., Hooper A.M., Pickett, J.A., Keep, N.H. and Field, L.M. (2009). Characterisation of Bombyx mori Odorant-binding Proteins Reveals that a General Odorant-binding Protein Discriminates Between Sex Pheromone Components. J. Mol. Biol. 389, 529-545.
Patel, P. Harris, R., Geddes, S.M., Strehle1, E.-M., Watson, J.D., Bashir, R., Bushby, K., Driscoll, P.C. and Keep, N.H. (2008). Solution Structure of the Inner DysF Domain of Myoferlin and Implications for Limb Girdle Muscular Dystrophy Type 2B J. Mol. Biol. 379, 981-990.
Garg, R. Riento, K. Keep, N.H., Morris, J.D.H. and Ridley A.J. (2008). N-terminus-mediated dimerization of ROCK-I is required for RhoE binding and actin reorganization. Biochemical Journal 411, 407-414
Guerrera, I. C, Keep, N. H and Godovac-Zimmermann, J. (2007). Proteomics Study Reveals Cross-Talk between Rho Guanidine Nucleotide Dissociation Inhibitor 1 Post-Translational Modifications in Epidermal Growth Factor Stimulated Fibroblasts. J. Proteome Res. 6, 2623-2630
Morris, J.R, Pagnon, L, Boutell, C, Katagiri, T., Keep, N.H and Solomon, E., (2006). Genetic analysis of BRCA1 ubiquitin ligase activity and its relationship to breast cancer susceptibility. Human Molecular Genetics 15, 599-606.
Keep, N.H., Ward, J.M, Robertson, G., Cohen-Gonsaud, M. and Henderson, B.M. (2006) Bacterial resuscitation factors: revival of viable but non-culturable bacteria Cellular and Molecular Life 63 2555-2559.
Keep, N.H., Ward, J.M, Cohen-Gonsaud, M. and Henderson, B.M. (2006). Wake up! Peptidoglycan lysis and bacterial non-growth states. Trends Microbiol. 14: 271-276
Kennaway, C.K., Benesch, J.L.P., Gohlke, U, Wang, L., Robinson, C.V., Orlova, E.V., Saibil, H.R. and. Keep, NH. (2005). Dodecameric structure of the small heat shock protein acr1 from Mycobacterium tuberculosis J.Biol. Chem. 280, 33419-33425.
Cohen-Gonsaud, M., Barthe, P, Bagnéris, C., Henderson, B., Ward, J. Roumestand, C. and Keep, N.H. (2005). The structure of a resuscitation-promoting factor from M.tuberculosis shows homology to lysozymes. Nature Structural and Molecular Biology 12, 270-273.
Cohen-Gonsaud, M., Barthe, P., Pommier; F., Harris, R., Driscoll, P.C., Keep, N.H. and Roumestand, C. (2004). Letter to the Editor: 1H, 15N, and 13C chemical shift assignments of the resuscitation promoting factor domain of Rv1009 from Mycobacterium tuberculosis. J. Biomol. NMR 30, 373-374
Harvey, K., Duguid, I.C., Alldred, M.J., Beatty, .S.E. , Ward, H., Keep, N.H., Lingenfelter, S.E., Pearce, B.R., Lundgren, J., Owen, M.J., Smart, T.G., Lüscher, B., Rees, M.I. and Harvey R.J. (2004). The GDP-GTP Exchange Factor Collybistin: An Essential Determinant of Neuronal Gephyrin Clustering. J. Neuroscience 24, 5816 -5826
Cohen-Gonsaud, M., Keep, N.H., Davies, A.P, Ward, J., Henderson, B. and Labesse, G. (2004) Resuscitation promoting factors possess a lysozyme-like domain. Trends in Biochemical Sciences 29, 7-10.
Garavini, H., Riento, K., Phelan, J.P., McAlister, M.S.B., Ridley, A.J. and Keep, N.H. (2002) Crystal Structure of the Core Domain of RhoE/Rnd3: A Constitutively Activated Small G Protein. Biochemistry 41, 6303 - 6310
Morris, J.R., Keep N.H. and Ellen Solomon E. (2002) Identification of residues required for the interaction of BARD1 with BRCA1 J. Biol. Chem. 277, 9382-9386.
Knight, D., Harris, R., McAlister M.S.B., Phelan, J.P., Geddes, S., Moss, S.J., Driscoll, P,C. and Keep, N.H. (2002). The X-ray crystal structure and putative ligand-derived peptide-binding properties of GABAA receptor associated protein (GABARAP). J. Biol. Chem. 277, 5556-5561
Harris, R., McAlister, M.S.B, Sankar, A., Phelan, J.P., Moss, S.J., Keep, N.H., and Driscoll, P.C. (2001) Backbone 1H, 13C, and 15N resonance assignments for a 14 kD protein, GABAA receptor associated protein (GABARAP). J. Biomol. NMR 21, 185-186.
Edwards, S.E. and Keep, N.H. (2001). The 2.7Å crystal structure of the activated FERM domain of moesin: an analysis of structural changes on activation. Biochemistry 40: 7061-7068.