Helen Saibil’s home page


Helen Saibil, FRS, FMedSci

Bernal Professor of Structural Biology

Crystallography, Department of Biological Sciences and ISMB

Birkbeck College, Malet St

London WC1E 7HX, UK

Email: h.saibil@mail.cryst.bbk.ac.uk


The Saibil group studies the operation of macromolecular machines using three-dimensional electron microscopy. Our research projects are in the areas of molecular chaperones and assisted protein folding/unfolding, misfolding into amyloid, and protein refolding in membrane pore formation. We use single particle cryo-electron microscopy and electron tomography to study isolated complexes, irregular assemblies and cell sections.


Research Interests

Some current projects

Earlier work

Birkbeck EM labhttp://people.cryst.bbk.ac.uk/~ubcg16z/empage.html
Review on 3D EM
Orlova & Saibil 
Chemical Reviewshttp://people.cryst.bbk.ac.uk/~ubcg16z/chemrevsmallfigs.pdf